To clear the auto complete cache in Outlook follow the below steps:
Outlook 2010
Method 1
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Open Outlook 2010.
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On the File tab, click Options.
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Click the Mail tab.
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Under Send Messages, click Empty Auto-Complete List.
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Click Yes.
Outlook will generate a new nickname cache.
Outlook 2002 through Outlook 2007
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Exit Outlook.
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Click Start, and then click Computer.
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Click Organize, and then click Folder and search options.
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On the View tab, click Show hidden files, folders, and drives.
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Click OK.
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Click Start, click All Programs, click Accessories, and then click Run.
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In the Run dialog box, type the following command (including the quotation marks), and then click OK:
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“C:\ Users\UserName\AppData\Roaming\Microsoft\Outlook” **Note Username in this path is the name of the currently logged on Windows user**
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Right-click the .NK2 file that has name of the profile that you want to reset, and then click Rename.
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Rename the file as profilename.bak, and then press Enter.
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Start Outlook.
Outlook will generate a new nickname cache.
Windows XP
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Exit Outlook.
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Click Start, and then click Search.
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In the Search Companion panel on the left, click All files or folders.
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In the All or part of the file name: box, type *.NK2.
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In the Look In box, click to select your local hard disk.
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Click More advanced options, and then click to select the Search hidden files and folders check box.
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Click Search.
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Right-click the .NK2 file that has the name of the profile that you want to reset, and then click Rename.
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Rename the file to profilename.bak, and then press Enter.
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Close Windows Explorer.
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Restart Outlook.
Outlook will generate a new nickname cache.
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